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The FANCJ/MutLα interaction is required for correction of the cross-link response in FA-J cells
FANCJ also called BACH1/BRIP1 was first linked to hereditary breast cancer through its direct interaction with BRCA1. FANCJ was also recently identified as a Fanconi anemia (FA) gene product, establishing FANCJ as an essential tumor suppressor. Similar to other FA cells, FANCJ-null (FA-J) cells accu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914102/ https://ncbi.nlm.nih.gov/pubmed/17581638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601754 |
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