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BOB.1/OBF.1 controls the balance of TH1 and TH2 immune responses

BOB.1/OBF.1 is a transcriptional coactivator essential at several stages of B-cell development. In T cells, BOB.1/OBF.1 expression is inducible by co-stimulation. However, a defined role of BOB.1/OBF.1 for T-cell function had not been discovered so far. Here, we show that BOB.1/OBF.1 is critical for...

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Autors principals: Brunner, Cornelia, Sindrilaru, Anca, Girkontaite, Irute, Fischer, Klaus-Dieter, Sunderkötter, Cord, Wirth, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914090/
https://ncbi.nlm.nih.gov/pubmed/17568779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601742
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