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BOB.1/OBF.1 controls the balance of TH1 and TH2 immune responses
BOB.1/OBF.1 is a transcriptional coactivator essential at several stages of B-cell development. In T cells, BOB.1/OBF.1 expression is inducible by co-stimulation. However, a defined role of BOB.1/OBF.1 for T-cell function had not been discovered so far. Here, we show that BOB.1/OBF.1 is critical for...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914090/ https://ncbi.nlm.nih.gov/pubmed/17568779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601742 |
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