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Regulation of BOB.1/OBF.1 stability by SIAH

The BOB.1/OBF.1 coactivator is critically involved in mediating octamer-dependent transcriptional activity in B lymphocytes. Mice lacking this coactivator show various defects in B-cell development, most notably they completely lack germinal centers. Consistent with this phenotype, BOB.1/OBF.1 level...

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Bibliografiska uppgifter
Huvudupphovsmän: Boehm, Jannic, He, Yunsheng, Greiner, Axel, Staudt, Louis, Wirth, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2001
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC149152/
https://ncbi.nlm.nih.gov/pubmed/11483518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4153
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