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Regulation of BOB.1/OBF.1 stability by SIAH
The BOB.1/OBF.1 coactivator is critically involved in mediating octamer-dependent transcriptional activity in B lymphocytes. Mice lacking this coactivator show various defects in B-cell development, most notably they completely lack germinal centers. Consistent with this phenotype, BOB.1/OBF.1 level...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149152/ https://ncbi.nlm.nih.gov/pubmed/11483518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4153 |
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