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Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex.

To test whether antibodies that are neutralizing or nonneutralizing for human immunodeficiency virus type 1 (HIV-1) primary isolates can be distinguished by their affinities for the oligomeric envelope glycoproteins, we selected HIV-1(JR-FL) as a model primary virus and a panel of 13 human monoclona...

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Bibliographic Details
Main Authors: Fouts, T R, Binley, J M, Trkola, A, Robinson, J E, Moore, J P
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191401/
https://ncbi.nlm.nih.gov/pubmed/9060632
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