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Regulation of MUC5AC expression by NAD(P)H:quinone oxidoreductase 1

Neutrophil elastase (NE), a potent neutrophil inflammatory mediator, increases MUC5AC mucin gene expression through undefined pathways involving reactive oxygen species. To determine the source of NE-generated reactive oxygen species, we used pharmacologic inhibitors of oxidoreductases to test wheth...

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Bibliographic Details
Main Authors: Zheng, Shuo, Byrd, Angela S., Fischer, Bernard M., Grover, Amy R., Ghio, Andrew J., Voynow, Judith A.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913945/
https://ncbi.nlm.nih.gov/pubmed/17395013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.01.040
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