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A multivalent minigene vaccine, containing B-cell, cytotoxic T-lymphocyte, and Th epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen.

The development of safe and effective vaccines remains a major goal in the prevention, and perhaps treatment, of infectious diseases. Ideally, a single vaccine would confer protection against several pathogens and would induce both cellular and humoral arms of the immune response. We originally demo...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: An, L L, Whitton, J L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032365/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.3.2292-2302.1997
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