A multivalent minigene vaccine, containing B-cell, cytotoxic T-lymphocyte, and Th epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen.

Eitemau Tebyg

• A recombinant minigene vaccine containing a nonameric cytotoxic-T-lymphocyte epitope confers limited protection against Listeria monocytogenes infection.
  gan: An, L L, et al.
  Cyhoeddwyd: (1996)
• Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection.
  gan: Klavinskis, L S, et al.
  Cyhoeddwyd: (1989)
• Molecular definition of a major cytotoxic T-lymphocyte epitope in the glycoprotein of lymphocytic choriomeningitis virus.
  gan: Whitton, J L, et al.
  Cyhoeddwyd: (1988)
• Induction of Protective Immunity to Listeria monocytogenes with Dendritic Cells Retrovirally Transduced with a Cytotoxic T Lymphocyte Epitope Minigene
  gan: Nakamura, Yutaro, et al.
  Cyhoeddwyd: (2003)
• DNA Immunization with Minigenes: Low Frequency of Memory Cytotoxic T Lymphocytes and Inefficient Antiviral Protection Are Rectified by Ubiquitination
  gan: Rodriguez, Fernando, et al.
  Cyhoeddwyd: (1998)