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Mathematical and Computational Analysis of Adaptation via Feedback Inhibition in Signal Transduction Pathways

We perform a systematic analysis of mechanisms of feedback regulation that underlie short-term adaptation in intracellular signaling systems. Upon receiving an external cue, these systems generate a transient response that quickly returns to basal levels even if the stimulus persists. Signaling path...

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Autori principali: Behar, Marcelo, Hao, Nan, Dohlman, Henrik G., Elston, Timothy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913166/
https://ncbi.nlm.nih.gov/pubmed/17513354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.107516
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