Herpes simplex virus immediate-early proteins ICP0 and ICP4 activate the endogenous human alpha-globin gene in nonerythroid cells.

Globin genes are normally expressed only in erythroid cell lineages. However, we found that the endogenous alpha-globin gene is activated following infection of human fibroblasts and HeLa cells with herpes simplex virus (HSV), leading to accumulation of correctly initiated transcripts driven by the...

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izdano v:	J Virol
Principais autores:	Cheung, P, Panning, B, Smiley, J R
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1997
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.3.1784-1793.1997
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