The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells.

Proteolytic activation of the precursor envelope glycoproteins gp160 of human immunodeficiency virus type 1 (HIV-1) and gp140 of HIV-2, a prerequisite for viral infection, results in the formation of gp120/gp41 and gp125/gp36, respectively. Cleavage is mediated by cellular proteases. Furin, a member...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Hallenberger, S, Moulard, M, Sordel, M, Klenk, H D, Garten, W
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1036-1045.1997
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