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The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells.

Proteolytic activation of the precursor envelope glycoproteins gp160 of human immunodeficiency virus type 1 (HIV-1) and gp140 of HIV-2, a prerequisite for viral infection, results in the formation of gp120/gp41 and gp125/gp36, respectively. Cleavage is mediated by cellular proteases. Furin, a member...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Hallenberger, S, Moulard, M, Sordel, M, Klenk, H D, Garten, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995623/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1036-1045.1997
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