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Synthetic inhibitors of endopeptidase EC 3.4.24.15: potency and stability in vitro and in vivo.

1. The role of the metalloendopeptidase EC 3.4.24.15 (EP 24.15) in peptide metabolism in vivo is unknown, in part reflecting the lack of a stable enzyme inhibitor. The most commonly used inhibitor, N-[1-(R,S)-carboxy-3-phenylpropyl]-Ala-Ala-Tyr-p-aminobenzoate (cFP-AAY-pAB, Ki = 16 nM), although sel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lew, R. A., Tomoda, F., Evans, R. G., Lakat, L., Boublik, J. H., Pipolo, L. A., Smith, A. I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909604/
https://ncbi.nlm.nih.gov/pubmed/8818353
Tagiau: Ychwanegu Tag
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