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Development and characterization of novel potent and stable inhibitors of endopeptidase EC 3.4.24.15.

Solid-phase synthesis was used to prepare a series of modifications to the selective and potent inhibitor of endopeptidase EC 3.4.24.15 (EP24.15), N-[1(R, S)-carboxy-3-phenylpropyl]-Ala-Ala-Tyr-p-aminobenzoate (cFP), which is degraded at the Ala-Tyr bond, thus severely limiting its utility in vivo....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shrimpton, C N, Abbenante, G, Lew, R A, Smith, I
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220764/
https://ncbi.nlm.nih.gov/pubmed/10620512
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