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Examination of the role of endopeptidase 3.4.24.15 in Aβ secretion by human transfected cells

1. We have taken advantage of our recent development of highly potent and specific phosphinic inhibitors of endopeptidase 3.4.24.15 to examine the putative contribution of the enzyme in the secretion of Aβ by HK293 transfected cells overexpressing the wild type and the Swedish (Sw) double mutated fo...

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Detalhes bibliográficos
Main Authors: Chevallier, Nathalie, Jiracek, Jirì, Vincent, Bruno, Baur, Claus-Peter, Spillantini, Maria-Gracia, Goedert, Michel, Dive, Vincent, Checler, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564707/
https://ncbi.nlm.nih.gov/pubmed/9179400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701151
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