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Effect of a novel selective and potent phosphinic peptide inhibitor of endopeptidase 3.4.24.16 on neurotensin-induced analgesia and neuronal inactivation
1. We have examined a series of novel phosphinic peptides as putative potent and selective inhibitors of endopeptidase 3.4.24.16. 2. The most selective inhibitor, Pro-Phe-Ψ(PO(2)CH(2))-Leu-Pro-NH(2) displayed a K(i) value of 12 nM towards endopeptidase 3.4.24.16 and was 5540 fold less potent on its...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1997
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564740/ https://ncbi.nlm.nih.gov/pubmed/9208137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701182 |
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