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Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat.

1. This study investigates the effects of the non-selective ETA/ETB receptor antagonist, SB 209670, on systemic haemodynamics, renal function, liver function, acid-base balance and survival in a rat model of endotoxic shock. 2. Injection of E. coli lipopolysaccharide (LPS, 10 mg kg-1, i.v.) resulted...

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Bibliografische gegevens
Hoofdauteurs: Ruetten, H., Thiemermann, C., Vane, J. R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909477/
https://ncbi.nlm.nih.gov/pubmed/8733596
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