In vivo pharmacological characterization of the non-peptide endothelin receptor antagonist SB 209670.

1. The aim of the present study was to assess the ability of SB 209670, a high affinity non-peptide endothelin receptor antagonist (0.4 and 18 nM Kis at human cloned ETA and ETB receptors, respectively), to inhibit the haemodynamic actions of endothelin-1 in vivo. 2. Systemic administration of (+/-)...

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Bibliografiska uppgifter
Huvudupphovsmän: Douglas, S A, Edwards, R M, Elliott, J D, Ohlstein, E H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510235/
https://ncbi.nlm.nih.gov/pubmed/7881741
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