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Selection of distinct conformational states of the 5-HT3 receptor by full and partial agonists.

1. 5-Hydroxytryptamine 5-HT3 receptor-mediated ion currents evoked by 5-HT, quaternary 5-HT (5-HTQ), meta-chlorophenylbiguanide (mCPBG), dopamine and tryptamine in N1E-115 mouse neuroblastoma cells have been investigated in whole-cell voltage clamp and single channel patch clamp experiments. 2. The...

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Main Authors: van Hooft, J. A., Vijverberg, H. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909396/
https://ncbi.nlm.nih.gov/pubmed/8851499
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