A cytotoxic nonstructural protein, NS1, of human parvovirus B19 induces activation of interleukin-6 gene expression.

We examined the biological function of a nonstructural regulatory protein, NS1, of human parvovirus B19. Because of the cytotoxic activity of NS1, human hematopoietic cell lines, K562, Raji, and THP-1, were established as transfectants which produce the viral NS1 protein upon induction by using bact...

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Detalhes bibliográficos
Main Authors: Moffatt, S, Tanaka, N, Tada, K, Nose, M, Nakamura, M, Muraoka, O, Hirano, T, Sugamura, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190939/
https://ncbi.nlm.nih.gov/pubmed/8970971
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