Human Parvovirus B19 Induces Cell Cycle Arrest at G(2) Phase with Accumulation of Mitotic Cyclins

Human parvovirus B19 infects specifically erythroid progenitor cells, which causes transient aplastic crises and hemolytic anemias. Here, we demonstrate that erythroblastoid UT7/Epo cells infected with B19 virus fall into growth arrest with 4N DNA, indicating G(2)/M arrest. These B19 virus-infected...

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Detalhes bibliográficos
Main Authors: Morita, Eiji, Tada, Kotaro, Chisaka, Hiroshi, Asao, Hironobu, Sato, Hiroyuki, Yaegashi, Nobuo, Sugamura, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114990/
https://ncbi.nlm.nih.gov/pubmed/11462027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7555-7563.2001
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