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Human Parvovirus B19 Induces Cell Cycle Arrest at G(2) Phase with Accumulation of Mitotic Cyclins

Human parvovirus B19 infects specifically erythroid progenitor cells, which causes transient aplastic crises and hemolytic anemias. Here, we demonstrate that erythroblastoid UT7/Epo cells infected with B19 virus fall into growth arrest with 4N DNA, indicating G(2)/M arrest. These B19 virus-infected...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Morita, Eiji, Tada, Kotaro, Chisaka, Hiroshi, Asao, Hironobu, Sato, Hiroyuki, Yaegashi, Nobuo, Sugamura, Kazuo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2001
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114990/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7555-7563.2001
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