A cytotoxic nonstructural protein, NS1, of human parvovirus B19 induces activation of interleukin-6 gene expression.

We examined the biological function of a nonstructural regulatory protein, NS1, of human parvovirus B19. Because of the cytotoxic activity of NS1, human hematopoietic cell lines, K562, Raji, and THP-1, were established as transfectants which produce the viral NS1 protein upon induction by using bact...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Moffatt, S, Tanaka, N, Tada, K, Nose, M, Nakamura, M, Muraoka, O, Hirano, T, Sugamura, K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8485-8491.1996
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