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Permeation enhancement of octreotide by specific bile salts in rats and human subjects: in vitro, in vivo correlations.

1. The potential of bile salts to improve the enteral absorption of octreotide, an orally active somatostatin analogue, was investigated by a combination of in vitro, in situ and in vivo experiments. 2. Incorporation of octreotide into lipid monolayers (as measured by area increase of the monolayer...

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Detalhes bibliográficos
Main Authors: Fricker, G., Fahr, A., Beglinger, C., Kissel, T., Reiter, G., Drewe, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909378/
https://ncbi.nlm.nih.gov/pubmed/8825366
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