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P-glycoprotein- and mrp2-mediated octreotide transport in renal proximal tubule

1. Transepithelial transport of a fluorescent derivative of octreotide (NBD-octreotide) was studied in freshly isolated, functionally intact renal proximal tubules from killifish (Fundulus heteroclitus). 2. Drug accumulation in the tubular lumen was visualized by means of confocal microscopy and was...

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Hlavní autoři: Gutmann, Heike, Miller, David S, Droulle, Agathe, Drewe, Jürgen, Fahr, Alfred, Fricker, Gert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571826/
https://ncbi.nlm.nih.gov/pubmed/10694230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703003
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