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Enteral absorption of octreotide: absorption enhancement by polyoxyethylene-24-cholesterol ether.

1. The somatostatin octapeptide-analogue octreotide was absorbed as an intact peptide from the gastro-intestinal tract with an absolute bioavailability of about 0.3% in rats. Administration of octreotide in the presence of polyoxyethylene (24)-cholesterol-ether (POECE) resulted in an about 23 fold i...

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Detalhes bibliográficos
Main Authors: Drewe, J., Fricker, G., Vonderscher, J., Beglinger, C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907992/
https://ncbi.nlm.nih.gov/pubmed/8448581
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