Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography.

1. Histamine H1 receptor occupancy in the human brain was measured in 20 healthy young men by positron emission tomography (PET) using [11C]-doxepin. 2. (+)-Chlorpheniramine, a selective and classical antihistamine, occupied 76.8 +/- 4.2% of the averaged values of available histamine H1 receptors in...

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Detalhes bibliográficos
Main Authors: Yanai, K., Ryu, J. H., Watanabe, T., Iwata, R., Ido, T., Sawai, Y., Ito, K., Itoh, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908925/
https://ncbi.nlm.nih.gov/pubmed/8564232
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