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Brain histamine H(1) receptor occupancy of orally administered antihistamines measured by positron emission tomography with (11)C-doxepin in a placebo-controlled crossover study design in healthy subjects: a comparison of olopatadine and ketotifen

AIMS: The strength of sedation due to antihistamines can be evaluated by using positron emission tomography (PET). The purpose of the present study is to measure histamine H(1) receptor (H(1)R) occupancy due to olopatadine, a new second-generation antihistamine and to compare it with that of ketotif...

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Bibliografiset tiedot
Päätekijät: Tashiro, Manabu, Mochizuki, Hideki, Sakurada, Yumiko, Ishii, Kenji, Oda, Keiichi, Kimura, Yuichi, Sasaki, Toru, Ishiwata, Kiichi, Yanai, Kazuhiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884984/
https://ncbi.nlm.nih.gov/pubmed/16390347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02514.x
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