Intrinsic activity of the non-prostanoid thromboxane A(2) receptor antagonist, daltroban (BM 13,505), in human platelets in vitro and in the rat vasculature in vivo

1 We evaluated the effects of daltroban on (i) human platelet shape change and aggregation in vitro, and (ii) mean systemic and pulmonary arterial pressures (MAP and MPAP, respectively) as well as haematocrit, in anaesthetized, open-chest Sprague-Dawley rats, compared with those of a chemically dist...

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Bibliografiska uppgifter
Huvudupphovsmän: Bertolino, Frédéric, Valentin, Jean-Pierre, Maffre, Myriam, Grelac, Françoise, Bessac, Anne-Marie, Maclouf, Jacques, Delhon, André, Lévy-Toledano, Sylviane, Patoiseau, Jean-François, Colpaert, Francis C., John, Gareth W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
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Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908744/
https://ncbi.nlm.nih.gov/pubmed/7647979
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