Antagonism of the thromboxane-prostanoid receptor is cardioprotective against right ventricular pressure overload

Abstract. Right ventricular (RV) failure is the primary cause of death in pulmonary arterial hypertension (PAH) and is a significant cause of morbidity and mortality in other forms of pulmonary hypertension. There are no approved therapies directed at preserving RV function. F-series and E-series is...

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Опубликовано в: :Pulm Circ
Главные авторы: West, James D., Voss, Bryan M., Pavliv, Leo, de Caestecker, Mark, Hemnes, Anna R., Carrier, Erica J.
Формат: Artigo
Язык:Inglês
Опубликовано: University of Chicago Press 2016
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869926/
https://ncbi.nlm.nih.gov/pubmed/27252848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/686140
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