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Investigation of the prostaglandin E (EP-) receptor subtype mediating relaxation of the rabbit jugular vein.

1. Prostaglandin E2 (PGE2) relaxes circular smooth muscle of the rabbit isolated jugular vein at very low concentrations (mean pIC50 against histamine-induced contraction = 9.34). This effect is not blocked by the EP1-receptor antagonist, AH 6809 (2 microM). 2. From a group of prostaglandin E analog...

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Main Authors: Lawrence, R. A., Jones, R. L.
格式: Artigo
語言:Inglês
出版: 1992
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908720/
https://ncbi.nlm.nih.gov/pubmed/1324050
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