Adenine nucleotide-induced inhibition of binding of sulphonylureas to their receptor in pancreatic islets.

1. The effects of the Mg complex of adenosine 5'-triphosphate (MgATP) on binding of sulphonylureas to microsomes obtained from mouse pancreatic islets were examined. 2. MgATP inhibited the binding of both glibenclamide and tolbutamide to microsomes. 3. Binding of [3H]-glibenclamide inhibited by...

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Main Authors: Schwanstecher, M., Löser, S., Brandt, C., Scheffer, K., Rosenberger, F., Panten, U.
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908451/
https://ncbi.nlm.nih.gov/pubmed/1628141
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