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Mutagenesis of the coxsackie B3 virus 2B/2C cleavage site: determinants of processing efficiency and effects on viral replication.

The enterovirus 2B/2C cleavage site differs from the common cleavage site motif AxxQ/G by the occurrence of either polar residues at the P1' position or large aliphatic residues at the P4 position. To study (i) the putative contribution of these aberrant residues to the stability of precursor protei...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: van Kuppeveld, F J, van den Hurk, P J, Zoll, J, Galama, J M, Melchers, W J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1996
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892883/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7632-7640.1996
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