Mutagenesis of the coxsackie B3 virus 2B/2C cleavage site: determinants of processing efficiency and effects on viral replication.

The enterovirus 2B/2C cleavage site differs from the common cleavage site motif AxxQ/G by the occurrence of either polar residues at the P1' position or large aliphatic residues at the P4 position. To study (i) the putative contribution of these aberrant residues to the stability of precursor protei...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	van Kuppeveld, F J, van den Hurk, P J, Zoll, J, Galama, J M, Melchers, W J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7632-7640.1996
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