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Insulin-Like Growth Factor Factor Binding Protein-2 is a Novel Mediator of p53 Inhibition of Insulin-Like Growth Factor Signaling

The p53 tumor suppressor induces cellular growth arrest and apoptosis in response to DNA damage by transcriptionally activating or repressing target genes and also through protein-protein interactions and direct mitochondrial activities. In 1995, insulin-like growth factor binding protein (IGFBP)-3...

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Autori principali: Grimberg, Adda, Coleman, Carrie M., Shi, Zonggao, Burns, Timothy F., MacLachlan, Timothy K., Wang, Wenge, El-Deiry, Wafik S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906874/
https://ncbi.nlm.nih.gov/pubmed/17102589
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