A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4.

The improvements to adenovirus necessary for an optimal gene transfer vector include the removal of virus gene expression in transduced cells, increased transgene capacity, complete replication incompetence, and elimination of replication-competent virus that can be produced during the growth of fir...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Brough, D E, Lizonova, A, Hsu, C, Kulesa, V A, Kovesdi, I
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190687/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8709289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.9.6497-6501.1996
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