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Protection of Mice Against Rotavirus Challenge following Intradermal DNA Immunization by Biojector Needle-Free Injection

Mucosal administration (intranasal or oral) of a VP6 rotavirus vaccine to mice consistently elicits high levels of protection after rotavirus challenge (93 – >99% reductions in fecal rotavirus shedding) but only when co-administered with an effective adjuvant such as LT(R192G). Here, we showed th...

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Detalhes bibliográficos
Main Authors: Choi, Anthony H.-C., Smiley, Kristi, Basu, Mitali, McNeal, Monica M., Shao, Mingyuan, Bean, Judy A, Clements, John D., Stout, Richard R., Ward, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906844/
https://ncbi.nlm.nih.gov/pubmed/17280754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.01.035
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