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Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor involved in the regulation of many cellular processes. We and others have previously shown that PPARγ activators display anti-inflammatory and chondroprotective properties in vitro and improve the clinical course and histopat...

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Autors principals: Afif, Hassan, Benderdour, Mohamed, Mfuna-Endam, Leandra, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Duval, Nicholas, Fahmi, Hassan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906809/
https://ncbi.nlm.nih.gov/pubmed/17386086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2151
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