A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis

The HLA-DRB1 gene was reported to be associated with anticitrullinated protein/peptide autoantibody (ACPA) production in rheumatoid arthritis (RA) patients. A new classification of HLA-DRB1 alleles, reshaping the shared epitope (SE) hypothesis, was recently found relevant in terms of RA susceptibili...

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Autors principals: Gourraud, Pierre-Antoine, Dieudé, Philippe, Boyer, Jean-Frédéric, Nogueira, Leonor, Cambon-Thomsen, Anne, Mazières, Bernard, Cornélis, François, Serre, Guy, Cantagrel, Alain, Constantin, Arnaud
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906795/
https://ncbi.nlm.nih.gov/pubmed/17328818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2131
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