New classification of HLA-DRB1 alleles in rheumatoid arthritis susceptibility: a combined analysis of worldwide samples

INTRODUCTION: Rheumatoid arthritis (RA) is a complex polygenic disease of unknown etiology. HLA-DRB1 alleles encoding the shared epitope (SE) (RAA amino acid pattern in positions 72 to 74 of the third hypervariable region of the DRβ1 chain) are associated with RA susceptibility. A new classification...

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Main Authors: Barnetche, Thomas, Constantin, Arnaud, Cantagrel, Alain, Cambon-Thomsen, Anne, Gourraud, Pierre-Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374469/
https://ncbi.nlm.nih.gov/pubmed/18307784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2379
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