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Murine glomerular mesangial cell uptake of apoptotic cells is inefficient and involves serum-mediated but complement-independent mechanisms

An increased number of apoptotic bodies have been detected in glomeruli of non-nephritic kidneys of C1q-deficient mice. In these mice an in vivo impaired uptake of apoptotic cells by peritoneal macrophages was also demonstrated. Here we investigated whether C1q plays a role in the in vitro clearance...

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Detalhes bibliográficos
Main Authors: CORTES-HERNANDEZ, J, FOSSATI-JIMACK, L, CARUGATI, A, POTTER, P K, WALPORT, M J, COOK, H T, BOTTO, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906558/
https://ncbi.nlm.nih.gov/pubmed/12452836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01998.x
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