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Nasal administration of CTB-insulin induces active tolerance against autoimmune diabetes in non-obese diabetic (NOD) mice
Nasal administration of beta cell-derived auto-antigens has been reported to suppress the development of autoimmune diabetes. We investigated the tolerogenic effects of insulin conjugated to the B subunit of cholera toxin (CTB). Nasal administration of 1 µg of CTB-insulin significantly delayed the i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2002
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1906515/ https://ncbi.nlm.nih.gov/pubmed/12390307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01988.x |
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