Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis

A T helper (Th) 1 immune response is important for host defense against tuberculosis. The multidrug resistance protein (Mrp) 1 is constitutively present at low levels on Th2 lymphocytes, and is expressed on Th1 lymphocytes upon activation. To determine the role of Mrp1 in the pathogenesis of tubercu...

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Библиографические подробности
Главные авторы: VERBON, A, LEEMANS, J C, WEIJER, S, FLORQUIN, S, VAN DER POLL, T
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2002
Предметы:
Animal Studies
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906484/
https://ncbi.nlm.nih.gov/pubmed/12296850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01952.x
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