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CpG Oligodeoxynucleotides Enhance Host Defense during Murine Tuberculosis

Oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs activate immune cells to produce cytokines. CpG ODNs protect mice against infections with intracellular bacteria by the induction of a T helper 1 (Th1) response. To determine the effect of CpG ODNs in pulmonary tuberculosis, mice were t...

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Detalhes bibliográficos
Main Authors: Juffermans, Nicole P., Leemans, Jaklien C., Florquin, Sandrine, Verbon, Annelies, Kolk, Arend H., Speelman, Peter, van Deventer, Sander J. H., van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127605/
https://ncbi.nlm.nih.gov/pubmed/11748176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.1.147-152.2002
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