CpG Oligodeoxynucleotides Enhance Host Defense during Murine Tuberculosis

Oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs activate immune cells to produce cytokines. CpG ODNs protect mice against infections with intracellular bacteria by the induction of a T helper 1 (Th1) response. To determine the effect of CpG ODNs in pulmonary tuberculosis, mice were t...

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Autores principales: Juffermans, Nicole P., Leemans, Jaklien C., Florquin, Sandrine, Verbon, Annelies, Kolk, Arend H., Speelman, Peter, van Deventer, Sander J. H., van der Poll, Tom
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC127605/
https://ncbi.nlm.nih.gov/pubmed/11748176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.1.147-152.2002
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