CpG Oligodeoxynucleotides Enhance Host Defense during Murine Tuberculosis

Oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs activate immune cells to produce cytokines. CpG ODNs protect mice against infections with intracellular bacteria by the induction of a T helper 1 (Th1) response. To determine the effect of CpG ODNs in pulmonary tuberculosis, mice were t...

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Main Authors: Juffermans, Nicole P., Leemans, Jaklien C., Florquin, Sandrine, Verbon, Annelies, Kolk, Arend H., Speelman, Peter, van Deventer, Sander J. H., van der Poll, Tom
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
主題:
Host Response and Inflammation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC127605/
https://ncbi.nlm.nih.gov/pubmed/11748176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.1.147-152.2002
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