The Th2-response in mercuric chloride-induced autoimmunity requires continuing costimulation via CD28*

Mercuric chloride (HgCl(2))-induced autoimmunity in Brown Norway (BN) rats is a highly polarized polyclonal Th2-driven autoimmune response with increased IgE production, lymphoproliferation, vasculitis and proteinuria. The increase in serum IgE concentration is clearly measurable by day 4 after the...

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Bibliografiska uppgifter
Huvudupphovsmän: Macphee, I A M, Turner, D R, Yagita, H, Oliveira, D B G
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2002
Ämnen:
Animal Studies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906466/
https://ncbi.nlm.nih.gov/pubmed/12197880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01928.x
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