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Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction.

Epstein-Barr virus (EBV) recombinants which carry three different deletion mutations in the LMP2A cytoplasmic amino-terminal domain were constructed. The presence of each mutation, LMP2A delta 21-36, LMP2A delta 21-64, and LMP2A delta 21-85, in EBV-infected transformed lymphoblastoid cell lines was...

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Publicado en:J Virol
Autores principales: Fruehling, S, Lee, S K, Herrold, R, Frech, B, Laux, G, Kremmer, E, Grässer, F A, Longnecker, R
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1996
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8709248/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.9.6216-6226.1996
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