PY Motifs of Epstein-Barr Virus LMP2A Regulate Protein Stability and Phosphorylation of LMP2A-Associated Proteins

Latent membrane protein 2A (LMP2A) is expressed in latent Epstein-Barr virus (EBV) infection. We have demonstrated that Nedd4 family ubiquitin-protein ligases (E3s), AIP4, WWP2/AIP2, and Nedd4, bind specifically to two PY motifs present within the LMP2A amino-terminal domain. In this study, LMP2A PY...

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Bibliografiske detaljer
Main Authors: Ikeda, Masato, Ikeda, Akiko, Longnecker, Richard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114286/
https://ncbi.nlm.nih.gov/pubmed/11356981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5711-5718.2001
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