The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential.

Using second-site homologous recombination, Epstein-Barr virus (EBV) recombinants were constructed which carry an LMP2A mutation terminating translation at codon 19. Despite the absence of LMP2A or LMP2A cross-reactive protein, the recombinants were able to initiate and maintain primary B-lymphocyte...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Longnecker, R, Miller, C L, Miao, X Q, Marchini, A, Kieff, E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC240138/
https://ncbi.nlm.nih.gov/pubmed/1328675
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items