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Autoantibodies against cytochrome P450s in sera of children treated with immunosuppressive drugs

Treatment with the immunosuppressive drugs cyclosporin and tacrolimus, the mainstays of anti-graft rejection and autoimmune disease therapy, is limited by their hepato-and nephrotoxicity. The metabolic conversion of these compounds to more easily excretable products is catalysed mainly by hepatic cy...

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Autori principali: LYTTON, S D, BERG, U, NEMETH, A, INGELMAN-SUNDBERG, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906342/
https://ncbi.nlm.nih.gov/pubmed/11876753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01754.x
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